home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
TIME: Almanac 1995
/
TIME Almanac 1995.iso
/
time
/
121189
/
12118900.068
< prev
next >
Wrap
Text File
|
1994-03-25
|
3KB
|
69 lines
<text id=89TT3278>
<title>
Dec. 11, 1989: Counterattack
</title>
<history>
TIME--The Weekly Newsmagazine--1989
Dec. 11, 1989 Building A New World
</history>
<article>
<source>Time Magazine</source>
<hdr>
HEALTH, Page 96
Counterattack
</hdr><body>
<p>Alpha-interferon becomes the first treatment for hepatitis C
</p>
<p> When it comes to hepatitis, doctors, like children, must
learn their ABCs. As they have long been taught, the
liver-destroying disease is caused by two distinct viruses,
known as A and B. But many patients show no signs of having been
exposed to either virus. Earlier this year scientists took a
significant step toward solving the riddle of non-A, non-B
hepatitis by moving on down the alphabet. They identified a
third virus that produces hepatitis and called it type C. Last
week researchers announced another milestone: the first
effective therapy for hepatitis C.
</p>
<p> Reporting in the New England Journal of Medicine, two
separate teams of scientists found that treatment with the drug
interferon halted destruction of liver cells in about half the
patients with chronic hepatitis. A total of 207 people were
studied by the two teams, one led by investigators at the
University of Florida, the other at the National Institute of
Diabetes, Digestive and Kidney Diseases.
</p>
<p> Patients received injections of interferon, a natural
infection-fighting protein that can be artificially produced by
genetically altered bacteria. One drawback: most of the
patients who improved suffered a relapse when the injections
ended. Doctors think the problem may be resolved by giving
interferon for longer periods or in higher doses. Says Dr. Saul
Krugman of New York University medical school: "There's no
question that it is very promising."
</p>
<p> Hepatitis C afflicts an estimated 150,000 Americans each
year. The virus, like type B, is spread primarily by sexual
activity and through tainted blood in transfusions or on
addicts' dirty needles. (Hepatitis A is passed along mainly
through contaminated foods.) Researchers at Chiron Corp., a
biotechnology firm in Emeryville, Calif., that first identified
the C virus, have devised a test for the pathogen that can be
used to screen the blood supply.
</p>
<p> Many of the people who contract hepatitis C never show
symptoms. But like Typhoid Mary, they become silent carriers of
the disease. About half those infected eventually suffer liver
damage. Some 15,000 patients a year develop cirrhosis, and a
small number may get cancer. That toll may be cut by interferon.
But doctors warn that the mystery of non-A, non-B hepatitis may
not be completely resolved. Type C virus could account for most
of these cases, but there is evidence that yet another
blood-borne virus will extend the hepatitis alphabet still
further.
</p>
</body></article>
</text>